| 產(chǎn)品編號(hào) | bs-2976R |
| 英文名稱(chēng) | GGT1 Rabbit pAb |
| 中文名稱(chēng) | γ谷氨酰轉(zhuǎn)移酶抗體 |
| 別 名 | CD224; gamma glutamyl transpeptidase; gamma glutamyltransferase 1; gamma glutamyltranspeptidase 1; gamma-glutamyltransferase 1; gamma-glutamyltranspeptidase 1 light chain; GGT 1; GGT; GGT1; GGT1_HUMAN; Glutamyl transpeptidase; GTG. |
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Specific References (1) | bs-2976R has been referenced in 1 publications.
[IF=2.52] Kobayashi S et al. γ-Glutamylcysteine synthetase and γ-glutamyl transferase as differential enzymatic sources of γ-glutamylpeptides in mice. Amino Acids. 2020 Apr;52(4):555-566. WB ; mouse.
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| 研究領(lǐng)域 | 細(xì)胞生物 信號(hào)轉(zhuǎn)導(dǎo) |
| 抗體來(lái)源 | Rabbit |
| 克隆類(lèi)型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | Human,Mouse,Rat |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 61 kDa |
| 檢測(cè)分子量 | |
| 細(xì)胞定位 | 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GGT1: 351-460/569 <Extracellular> |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Initiates extracellular glutathione (GSH) breakdown, provides cells with a local cysteine supply and contributes to maintain intracelular GSH level. It is part of the cell antioxidant defense mechanism. Catalyzes the transfer of the glutamyl moiety of glutathione to amino acids and dipeptide acceptors. Alternatively, glutathione can be hydrolyzed to give Cys-Gly and gamma glutamate. Isoform 3 seems to be inactive. Tissue specificity: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein. Subunit: Heterodimer composed of the light and heavy chains. The active site is located in the light chain. Subcellular Location: Membrane; Single-pass type II membrane protein. Tissue Specificity: Detected in fetal and adult kidney and liver, adult pancreas, stomach, intestine, placenta and lung. Isoform 3 is lung-specific. There are several other tissue-specific forms that arise from alternative promoter usage but that produce the same protein. Similarity: Belongs to the gamma-glutamyltransferase family. SWISS: P19440 Gene ID: 2678 Database links: Entrez Gene: 2678 Human Entrez Gene: 14598 Mouse Omim: 612346 Human SwissProt: P19440 Human SwissProt: Q60928 Mouse Unigene: 595809 Human Unigene: 645535 Human Unigene: 4559 Mouse Unigene: 10010 Rat |
| 產(chǎn)品圖片 |
Sample:
Lane 1: Mouse kidney lysates
Lane 2: Mouse Stomach lysates
Lane 3: Mouse Large intestine lysates
Primary: Anti-GGT1 (bs-2976R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kDa
Observed band size: 61 kDa
Sample:
Lane 1: Liver (Mouse) Tissue Lysate at 40 ug
Lane 2: Liver (Rat) Tissue Lysate at 40 ug
Lane 3: Thymus (Rat) Tissue Lysate at 40 ug
Lane 4: A549 (Human) Cell Lysate at 30 ug
Lane 5: U937 (Human) Cell Lysate at 30 ug
Lane 6: HepG2 (Human) Cell Lysate at 30 ug
Primary: Anti-GGT1 (bs-2976R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 61 kD
Sample: 293T Cell (Human) Lysate at 40 ug
Primary: Anti-GGT1 (bs-2976R) at 1/300 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 61 kD
Observed band size: 61 kD
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