| 產(chǎn)品編號(hào) | bs-16005R |
| 英文名稱 | FAM57B Rabbit pAb |
| 中文名稱 | FAM57B蛋白抗體 |
| 別 名 | CORD22; FAM57B; FP1188; 1500016O10Rik; A330104J06Rik; RGD1308215; TLC3B_HUMAN; TLCD3B; Protein FAM57B; TLC domain-containing protein 3B; 2.3.1.-; TLC3B_MOUSE; |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 克 隆 號(hào) | |
| 交叉反應(yīng) | (predicted: Human,Mouse,Rat,Pig,Sheep,Cow,Horse) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:100-500,IHC-F=1:100-500,IF=1:100-500,ICC/IF=1:100-500
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 31 kDa |
| 細(xì)胞定位 | 細(xì)胞漿 細(xì)胞膜 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FAM57B: 21-120/559 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3% of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The FAM57B gene product has been provisionally designated FAM57B pending further characterization. Subcellular Location: Membrane. Similarity: Contains 1 TLC (TRAM/LAG1/CLN8) domain. SWISS: Q71RH2 Gene ID: 83723 Database links: Entrez Gene: 83723 Human Entrez Gene: 100066097 Horse Entrez Gene: 68952 Mouse Omim: 615175 Human SwissProt: Q71RH2 Human SwissProt: Q7TNV1 Mouse Unigene: 558560 Human Unigene: 440393 Mouse Unigene: 128103 Rat |
