| 產(chǎn)品編號 | bs-17711R |
| 英文名稱 | Rabbit Anti-MON1A antibody |
| 中文名稱 | MON1A蛋白抗體 |
| 別 名 | FLJ97088; MGC13272; MON1 homolog A; MON1A; MON1A_HUMAN; SAND1; Vacuolar fusion protein MON1 homolog A. |
| 研究領(lǐng)域 | 細(xì)胞生物 信號轉(zhuǎn)導(dǎo) 細(xì)胞凋亡 轉(zhuǎn)運(yùn)蛋白 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Human,Mouse (predicted: Rat,Rabbit,Pig,Sheep,Cow,Horse,Plants, Cynomolgus Monkey) |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 62kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human MON1A: 51-150/555 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
MON1A is a 555 amino acid protein that exists as multiple alternatively spliced isoforms and plays an important role in membrane trafficking, specifically through the secretory apparatus. The gene encoding MON1A maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan Syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth Disease are a few of the numerous genetic diseases associated with chromosome 3. Function: Plays an important in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Similarity: Belongs to the MON1/SAND family. SWISS: Q86VX9 Gene ID: 84315 Database links: Entrez Gene: 84315 Human Entrez Gene: 72825 Mouse Omim: 611464 Human SwissProt: Q86VX9 Human SwissProt: Q6PDG8 Mouse Unigene: 655014 Human Unigene: 38037 Mouse |
| 產(chǎn)品圖片 |
Sample:
Lane 1: 293T (Human) Cell Lysate at 30 ug
Lane 2: Hela (Human) Cell Lysate at 30 ug
Primary: Anti-MON1A (bs-17711R) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Rabbit IgG at 1/20000 dilution
Predicted band size: 70/55 kD
Observed band size: 70/50 kD
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