| 產(chǎn)品編號(hào) | bsm-51513M |
| 英文名稱(chēng) | Mouse Anti-HNMT antibody |
| 中文名稱(chēng) | 組織胺N-甲基轉(zhuǎn)移酶單克隆抗體 |
| 別 名 | EC 2.1.1.8; Histamine N methyltransferase; Histamine N-methyltransferase; HMT; HNMT S1; HNMT S2; HNMT_HUMAN. |
| 研究領(lǐng)域 | 細(xì)胞生物 神經(jīng)生物學(xué) |
| 抗體來(lái)源 | Mouse |
| 克隆類(lèi)型 | Monoclonal |
| 克 隆 號(hào) | FB12H1 |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 | WB=1:500-2000
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 33kDa |
| 細(xì)胞定位 | 細(xì)胞漿 |
| 性 狀 | Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | Recombinant human HNMT (Fragment) (His-tagged). |
| 亞 型 | IgG1 |
| 純化方法 | affinity purified by Protein G |
| 緩 沖 液 | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| 保存條件 | Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 |
Calcitonin is a 32 amino acid peptide hormone synthesized by the parafollicular cells of the thyroid. It causes a rapid, but short lived, reduction in serum calcium and phosphate by promoting the incorporation of those ions in the bones. This effect is opposite to that of parathyroid hormone. Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors. Staining for calcitonin in medullary carcinoma of the thyroid produces a fine granular pattern in the cytoplasm. Amyloid deposits within the tumor may also exhibit varying degrees of calcitonin activity. Function: Inactivates histamine by N-methylation. Plays an important role in degrading histamine and in regulating the airway response to histamine. Subcellular Location: Cytoplasm. Similarity: Belongs to the methyltransferase superfamily. HNMT family. SWISS: P50135 Gene ID: 3176 Database links:
Entrez Gene: 3176 Human SwissProt: P50135 Human
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| 產(chǎn)品圖片 |
Sample:
Lane 1: HepG2 cell lysates
Primary: Anti-HNMT (bsm-51513M) at 1/1000 dilution
Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution
Predicted band size: 33 kD
Observed band size: 28 kD
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