| 產(chǎn)品編號 |
bs-43030P |
| 英文名稱 |
Recombinant mouse CD40L protein, His (HEK293)
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| 中文名稱 |
重組小鼠CD40L蛋白 |
| 別 名 |
TNFSF5; CD 154; CD154; CD 40L; CD154; CD154 antigen; CD40 homologue; CD40 ligand; CD40LG; gp39; hCD40L; HIGM1; Hyper IgM syndrome; IGM; IMD3; Ly62; T B cell activating molecule; T cell antigen GP39; TBAM; TNF related activation protein; TNF superfamily member 5; Tnfsf5; TRAP; Tumor necrosis factor (ligand) superfamily member 5; CD40L_MOUSE; Recombinant mouse CD40L protein, His (HEK293) |
| 克 隆 號 |
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| 理論分子量 |
20 kDa |
| 檢測分子量 |
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| 性 狀 |
Lyophilized or Liquid |
| 濃 度 |
＞0.5 mg/ml |
| 物 種 |
Mouse |
| 序 列 |
112-260/260 |
| 純 度 |
>95% as determined by SDS-PAGE |
| 純化方法 |
AC |
| 內(nèi)毒素 |
Not analyzed |
| 表達系統(tǒng) |
HEK293 cell |
| 活性 |
Yes |
| 標簽 |
His |
| 緩 沖 液 |
PBS (pH7.4). |
| 保存條件 |
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事項 |
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
CD40 ligand (CD40L) is a 33 kDa type II membrane glycoprotein expressed mainly on the cell surface of activated T lymphocytes, but also exists as a soluble form extracellularly. CD40L is the ligand for CD40, a member of the TNF superfamily, which is expressed on the cell surface of B cells, macrophages/monocytes, dendritic cells, vascular endothelial cells, and epithelial cells. CD40L plays an important role in B cell proliferation, antibody class switching, modulation of apoptosis in the germinal center through interaction with B cells expressing CD40, and activation of CD4+ T cells. Mutation within the CD40L gene is linked to hyper IgM syndrome, an X linked immunodeficiency disease that is characterized by elevated level of serum IgM and decreased level of other isotypes.
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| 產(chǎn)品圖片 |
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.
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