產(chǎn)品編號(hào) | D51751 |
英文名稱 | Takinib |
中文名稱 | |
別 名 | TAK1抑制劑 |
克 隆 號(hào) | |
CAS | 1111556-37-6 |
理論分子量 | 322.36 kDa |
檢測(cè)分子量 | |
性 狀 | Lyophilized |
保存條件 | Store in dry, dark place for one year. |
注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
產(chǎn)品介紹 |
Takinib is a selective TAK1 inhibitor that induces apoptosis following TNF-α stimulation in cell models of rheumatoid arthritis and metastatic breast cancer. Takinib is an inhibitor of autophosphorylated and non-phosphorylated TAK1 that binds within the ATP-binding pocket and inhibits by slowing down the rate-limiting step of TAK1 activation. |