| 產(chǎn)品編號 | BIO0903SM |
| 英文名稱 | Anti-human TROP2 (Sacituzumab-MMAE Biosimilar) |
| 中文名稱 | |
| 抗體來源 | |
| 克隆類型 | Monoclonal |
| 交叉反應(yīng) | Human |
| 產(chǎn)品應(yīng)用 |
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 理論分子量 | 150 kDa |
| 檢測分子量 | |
| 性 狀 | Lyophilized |
| 亞 型 | Human IgG1 |
| 純化方法 | Protein A |
| 保存條件 | For long term storage, the produce should be stored at -20°C or lower. |
| 注意事項 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| PubMed | PubMed |
| 產(chǎn)品介紹 | |
| 產(chǎn)品圖片 |
Killing assay test on NCL-H292 Cells,the maximum kill rate of anti-TROP2 Reference Antibody (Sacituzumab MMAE) is about 100%.
Sacituzumab-ADC inhibited the tumor growth of MDA-MB-231 on NSG mice. The result showed significant anti-tumor effects, with an tumor inhibition rate (TGI) of 80.0% at 5 mpk at D37.
The purity of Anti-TROP2 Reference Antibody (Sacituzumab-MMAE) is more than 95%, determined by SEC-HPLC.
Anti-TROP2 Reference Antibody (Sacituzumab-MMAE) on SDS-PAGE under reducing (R) condition. The purity of the protein is greater than 90%.
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