| 產(chǎn)品編號(hào) | bs-43746P |
| 英文名稱 | Recombinant human ALK protein, C-His (HEK293) |
| 中文名稱 | 重組人間變型淋巴瘤激酶蛋白 |
| 別 名 | ALK tyrosine kinase receptor; ALK tyrosine kinase receptor precursor; ALK/EML4 fusion gene, included; ALK/NPM1 fusion gene, included; anaplastic lymphoma kinase(Ki-1); Anaplastic lymphoma kinase; Anaplastic lymphoma kinase Ki 1; Anaplastic lymphoma kinase Ki1; Anaplastic lymphoma kinase p80; CD 246; CD246; CD-246; CD246 antigen; EC 2.7.10.1; Ki 1; Ki1; NBLST3; Tcrz; TFG/ALK. |
| 克 隆 號(hào) | |
| 理論分子量 | 112.3 kDa |
| 檢測(cè)分子量 | |
| 性 狀 | Liquid |
| 濃 度 | >1mg/ml |
| 純 度 | >90% as determined by SDS-PAGE |
| 緩 沖 液 | PBS (pH=7.4) |
| 保存條件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事項(xiàng) | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 產(chǎn)品介紹 |
This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily. This protein comprises an extracellular domain, an hydrophobic stretch corresponding to a single pass transmembrane region, and an intracellular kinase domain SWISS: Q9UM73 Gene ID: 238 ALK蛋白在細(xì)胞生長(zhǎng)調(diào)控中起重要作用，主要表達(dá)在神經(jīng)細(xì)胞,白細(xì)胞癌基因蛋白。 ALK p80是多向性生長(zhǎng)因子酪氨酸激酶受體蛋白， 間變性大細(xì)胞淋巴瘤伴有t(2;5) (p23;q35)染色體的易位，易位后的細(xì)胞基因表達(dá)分子量為80kD，常伴有CD30陽(yáng)性，ALK p80陽(yáng)性的間變性大細(xì)胞淋巴瘤預(yù)后好于陰性病例。 主要用于間變性大細(xì)胞淋巴瘤與何杰金氏淋巴瘤的鑒別診斷，間變性大細(xì)胞淋巴瘤中陽(yáng)性率大約為70%左右，還可以用于骨髓中間變性大細(xì)胞淋巴瘤的診斷. |
| 產(chǎn)品圖片 |
The purity of the protein is greater than 85% as determined by reducing SDS-PAGE.
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