| 產(chǎn)品編號(hào) | bs-8074R-AP |
| 英文名稱 | Rabbit Anti-ANKRD1/AP Conjugated antibody |
| 中文名稱 | 堿性磷酸酶（AP）標(biāo)記的心肌錨蛋白重復(fù)結(jié)構(gòu)域1抗體 |
| 別 名 | ALRP; ANKR1_HUMAN; ANKRD 1; ANKRD1; Ankyrin repeat domain 1 (cardiac muscle); Ankyrin repeat domain containing protein 1; Ankyrin repeat domain-containing protein 1; C 193; C193; Cardiac ankyrin repeat protein; CARP; CVARP; Cytokine inducible nuclear protein; Cytokine-inducible gene C-193 protein; Cytokine-inducible nuclear protein; HA1A2; Liver ankyrin repeat domain 1; MCARP. |
| 規(guī)格價(jià)格 | 100ul/2980元 購(gòu)買 大包裝/詢價(jià) |
| 說(shuō) 明 書 | 100ul |
| 研究領(lǐng)域 | 腫瘤 心血管 細(xì)胞生物 免疫學(xué) 信號(hào)轉(zhuǎn)導(dǎo) 轉(zhuǎn)錄調(diào)節(jié)因子 表觀遺傳學(xué) |
| 抗體來(lái)源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Pig, Cow, Rabbit, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:50-200 IHC-F=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 36kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human ANKRD1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲(chǔ) 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Function: May play an important role in endothelial cell activation. May act as a nuclear transcription factor that negatively regulates the expression of cardiac genes. Induction seems to be correlated with apoptotic cell death in hepatoma cells. Subunit: Interacts with YBX1 (By similarity). Interacts with TTN/titin. Subcellular Location: Nucleus. Tissue Specificity: Mainly expressed in activated vascular endothelial cells. To a lower extent, also expressed in hepatoma cells. DISEASE: Defects in ANKRD1 may be a cause of total anomalous pulmonary venous return (TAPVR) . TAPVR is a rare congenital heart disease (CHD) in which the pulmonary veins fail to connect to the left atrium during cardiac development, draining instead into either the right atrium or one of its venous tributaries. This disease accounts for 1.5% of all CHDs and has a prevalence of approximately 1 out of 15'000 live births. Similarity: Contains 5 ANK repeats. Database links: Entrez Gene: 27063 Human Entrez Gene: 107765 Mouse Omim: 609599 Human SwissProt: Q15327 Human SwissProt: Q9CR42 Mouse Unigene: 448589 Human Unigene: 10279 Mouse Unigene: 3789 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
