| 產(chǎn)品編號 | bs-16276R-Gold |
| 英文名稱 | Rabbit Anti-GPIHBP1/Gold Conjugated antibody |
| 中文名稱 | 膠體金標(biāo)記的高密度脂蛋白結(jié)合蛋白1抗體 |
| 別 名 | Glycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1; GPI anchored HDL binding protein 1; GPI anchored High Density Lipid binding protein 1; GPI HBP1; GPI-anchored HDL-binding protein 1; GPI-HBP1; GPIHBP1; Hbp1; HDBP1_HUMAN; High density lipoprotein-binding protein 1. |
| 規(guī)格價格 | 100ul/2980元 購買 大包裝/詢價 |
| 說 明 書 | 100ul（10nm 15nm 35nm） |
| 研究領(lǐng)域 | 腫瘤 心血管 細胞生物 免疫學(xué) |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | (predicted: Human, ) |
| 產(chǎn)品應(yīng)用 | IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 18kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 0.4mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GPIHBP1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300. |
| 保存條件 | Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles. |
| 產(chǎn)品介紹 |
background: GPIHBP1 (glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1) is a capillary endothelial cell protein that provides a platform for LPL-mediated processing of chylomicrons. Consisting of 184 amino acids, GPIHBP1 is a single-pass membrane protein that may be regulated by dietary factors and by PPARγ. Mutations in the gene encoding GPIHBP1 are linked to chylomicronemia syndrome, a rare genetic disorder caused by LPL deficiency and is characterized by enlarged liver and spleen, inflammation of the pancreas, fatty deposits under the skin and possibly deposits in the retina of the eye. Function: Plays a key role in the lipolytic processing of chylomicrons. Subunit: Binds with high affinity to high-density lipoprotein (HDL) (By similarity). Binds to lipoprotein lipase (LPL), chylomicrons and APOA5. Subcellular Location: Cell membrane. Localized at the cell surface. Post-translational modifications: Glycosylation of Asn-78 is critical for cell surface localization and the binding of chylomicrons and lipoprotein lipase (By similarity). Similarity: Contains 1 UPAR/Ly6 domain. Database links: Entrez Gene: 338328 Human SwissProt: Q8IV16 Human Unigene: 426410 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
