| 產(chǎn)品編號 | bs-18831R-HRP |
| 英文名稱 | Rabbit Anti-RPS6KC1/HRP Conjugated antibody |
| 中文名稱 | 辣根過氧化物酶標(biāo)記的p52核糖體蛋白S6激酶抗體 |
| 別 名 | p52 S6 kinase; 52 kDa ribosomal protein S6 kinase; humS6PKh1; KS6C1_HUMAN; Ribosomal protein S6 kinase 52kD polypeptide 1; Ribosomal protein S6 kinase 52kDa polypeptide 1; Ribosomal protein S6 kinase delta 1; Ribosomal protein S6 kinase delta-1; Ribosomal S6 kinase like protein with two PSK domains 118 kDa protein; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; RPK 118; RPK118; RPS6KC1; S6K-delta-1; SPHK1 binding protein; SPHK1-binding protein. |
| 規(guī)格價(jià)格 | 100ul/2980元 購買 大包裝/詢價(jià) |
| 說 明 書 | 100ul |
| 研究領(lǐng)域 | 細(xì)胞生物 免疫學(xué) 信號轉(zhuǎn)導(dǎo) 激酶和磷酸酶 |
| 抗體來源 | Rabbit |
| 克隆類型 | Polyclonal |
| 交叉反應(yīng) | Mouse, (predicted: Human, Rat, Pig, Cow, Horse, Sheep, ) |
| 產(chǎn)品應(yīng)用 | IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200
not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 119kDa |
| 性 狀 | Lyophilized or Liquid |
| 濃 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human RPS6KC1 |
| 亞 型 | IgG |
| 純化方法 | affinity purified by Protein A |
| 儲 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存條件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 產(chǎn)品介紹 |
background: p52 S6 kinase, also known as RPS6KC1 (ribosomal protein S6 kinase, 52kDa, polypeptide 1) or RPK118, is a 1,066 amino acid member of the Ser/Thr kinase family that localizes to both the cytoplasm and the nucleus and contains one MIT domain, one PX domain and two protein kinase domains. Expressed at high levels in brain, placenta, heart, testis, kidney, liver and skeletal muscle, p52 S6 kinase catalyzes the ATP-dependent phosphorylation of target proteins and is thought to be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Function: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. Subcellular Location: Cytoplasm. Membrane. Also found in some small dot-like or ring-shaped early endosome structures. Tissue Specificity: Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon. Similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. Contains 1 MIT domain. Contains 2 protein kinase domains. Contains 1 PX (phox homology) domain. Database links: Entrez Gene: 26750 Human Entrez Gene: 320119 Mouse GenBank: NP_001129610.1 Human GenBank: NP_036556.2 Human SwissProt: Q96S38 Human SwissProt: Q8BLK9 Mouse Unigene: 591416 Human Unigene: 220912 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
